In this episode, I’ll discuss amiodarone induced hepatotoxicity. Subscribe on iTunes, Android, or Stitcher Amiodarone is known to cause two distinct types of hepatoxicity: 1. Hepatotoxicity associated with long-term oral therapy 2. Hepatotoxicity associated with intravenous amiodarone Hepatotoxicity associated with long-term oral therapy Almost one-quarter of patients on long-term oral amiodarone therapy experience an asymptomatic […]

In this episode I’ll: 1. Discuss an article about using inhaled volatile agents for ICU sedation. 2. Answer the drug information question “Should IV or oral antihypertensives be used for severe hypertension in the immediate period after acute ischemic stroke?” 3. Share a resource for reversal of antithrombotics in intracranial hemorrhage. Subscribe on iTunes, Android, […]

In this episode, I’ll discuss scenarios where dexmedetomidine & etomidate are better than ketamine. Subscribe on iTunes, Android, or Stitcher Strictly referring to therapeutic uses, ketamine is a stylish medication to use and to talk about using. It has been FDA approved for over 45 years, but ketamine’s popularity as measured by published journal articles […]

In this episode I’ll: 1. Discuss an article about delayed sequence intubation. 2. Answer the drug information question “Can posaconazole cause hypokalemia?” 3. Share a resource for the Board Certified Critical Care Pharmacy (BCCCP) exam. Subscribe on iTunes, Android, or Stitcher My on-line Critical Care Pharmacy Academy will open December 2016. The Academy will be […]

In this episode, I’ll discuss the role of sodium bicarbonate in critically ill patients. Subscribe on iTunes, Android, or Stitcher At the time of this episode, I am hosting a closed beta program for my Critical Care Pharmacy Academy, a private, paid membership group where I teach other pharmacists about critical care. I plan to […]

In this episode I’ll: 1. Discuss an article about the combination of vancomycin and piperacillin-tazobactam and the development of acute kidney injury. 2. Answer the drug information question “When using steroids for the treatment of septic shock, should they be abruptly stopped or tapered?” 3. Share a resource for remembering antibiotic sensitivity. Subscribe on iTunes, […]

In this episode, I will discuss the use of midodrine to wean ICU patients off of vasopressor infusions. Subscribe on iTunes, Android, or Stitcher At the time of this episode, I am hosting a closed beta program for my Critical Care Pharmacy Academy, a private, paid membership group where I teach other pharmacists about critical […]

In this episode I’ll: 1. Discuss an article about levosimendan in sepsis. 2. Answer the drug information question “Should catecholamines be started before intubating a patient with severe pulmonary hypertension?” 3. Share a resource about how to become a peer-reviewer for a medical journal. Subscribe on iTunes, Android, or Stitcher The Critical Care Pharmacy Academy […]

In this episode, I’ll discuss stress ulcer prophylaxis in critically ill patients. Subscribe on iTunes, Android, or Stitcher Stress ulcers were first described in 1969. Stress ulcers are thought to form due to hypoperfusion to the gastric mucosa associated with critical illness. Various factors including coagulopathy, history of peptic ulcer disease, and prolonged mechanical ventilation […]

In this episode I’ll: 1.   Discuss an article about the hemodynamic effects of IV acetaminophen in critically ill patients. 2.  Answer the drug information question “When should an opioid naive patient receive a continuous basal rate on patient-controlled analgesia?” 3.  Share a resource for easily extracting ICD-10 codes from natural text. Subscribe on iTunes, […]

In this episode I’ll: 1. Discuss an article about the adverse outcomes of calcium administration in critically ill patients. 2. Answer the drug information question “What dose of sulfamethoxazole/trimethoprim should be used to treat stenotrophomonas in a super-morbidly obese patient?” 3. Share a resource I’ve used to convert heparin protocols to anti-Xa monitoring. Subscribe on […]