In this episode, I’ll discuss why hypotonic or dextrose-based solutions are avoided in patients with acute ischemic stroke. Subscribe on iTunes, Android, or Stitcher A common cause of in-hospital death from acute ischemic stroke is brain edema and elevated intracranial pressure. This is often a result of occlusion of the major intracranial arteries or multi-lobar […]

In this episode, I’ll discuss deresuscitation of patients in the ICU. Subscribe on iTunes, Android, or Stitcher Since the first Surviving Sepsis Campaign, guidelines have contained a strong emphasis on early and aggressive fluid resuscitation for patients in septic shock. While this focus on fluid resuscitation is widely regarded as a cornerstone of the treatment […]

In this episode, I’ll discuss why the adenosine dose is reduced by 50% when it is given in a central line. Subscribe on iTunes, Android, or Stitcher   The recommendation to reduce the initial dose of adenosine from 6 mg to 3 mg and follow-up doses from 12 mg to 6 mg when it is given […]

In this episode, I’ll discuss an article about using gabapentin for severe alcohol withdrawal. Subscribe on iTunes, Android, or Stitcher Article High‐Dose Gabapentin for the Treatment of Severe Alcohol Withdrawal Syndrome: A Retrospective Cohort Analysis Lead author: Alexander Levine Published in the journal Pharmacotherapy July 2019 Background Gabapentin has beneficial effects on treating patients with […]

Thank you for being a listener of The Elective Rotation – a Critical Care and Hospital Pharmacy Podcast. I am celebrating 4 years of this podcast, and it is 100% supported by listeners just like you. Unlike many other professional resources, there are no third-party sponsors or advertisers on this podcast, at pharmacyjoe.com, or in […]

Thank you for being a listener of The Elective Rotation – a Critical Care and Hospital Pharmacy Podcast. I am celebrating 4 years of this podcast, and it is 100% supported by listeners just like you. Unlike many other professional resources, there are no third-party sponsors or advertisers on this podcast, at pharmacyjoe.com, or in […]

In this episode, I’ll discuss when the acute ischemic stroke guidelines recommend stopping alteplase mid-infusion. Subscribe on iTunes, Android, or Stitcher There are three circumstances where AHA acute ischemic stroke guidelines recommend stopping alteplase mid-infusion. 1. Abnormal pre-alteplase coagulation test results become available Coagulation studies are no longer necessary to decide whether or not to […]

In this episode, I’ll discuss an article about the adverse effects of medications given for acute agitation in the ED. Subscribe on iTunes, Android, or Stitcher Article Risk Factors for Sedation‐Related Events During Acute Agitation Management in The Emergency Department Lead author: Celene Y.L. Yap Published in Academic Emergency Medicine July 2019 Background Sedation for […]

In this episode, I’ll discuss why you don’t need to know the cause of severe, symptomatic hyponatremia before treating it. Subscribe on iTunes, Android, or Stitcher Severe, symptomatic hyponatremia is characterized by a serum sodium < 125 mEq/L and symptoms such as seizure, mental status changes, respiratory depression, coma or obtundation. Without immediate treatment, this […]

In this episode, I’ll discuss the final 4 questions of a recent survey of intensive care professionals about clinically relevant pharmacokinetic knowledge on antibiotic dosing. This is part 3 of a 3 part series that began with episode 414. Subscribe on iTunes, Android, or Stitcher The survey was published in May 2019 in the journal […]

In this episode, I’ll discuss questions 6, 7 and 8 of a recent survey of intensive care professionals about clinically relevant pharmacokinetic knowledge on antibiotic dosing. This is part 2 of a 3 part series that began with episode 414. Subscribe on iTunes, Android, or Stitcher The survey was published in May 2019 in the […]

In this episode, I’ll discuss a recent survey of intensive care professionals about clinically relevant pharmacokinetic knowledge on antibiotic dosing. Subscribe on iTunes, Android, or Stitcher Article Clinically relevant pharmacokinetic knowledge on antibiotic dosing among intensive care professionals is insufficient: a cross-sectional study Lead author: Lucas M. Fleuren Published May 2019 in the journal Critical Care […]