In this episode I’ll: 1. Discuss an article comparing half-dose versus full-dose alteplase for the treatment of pulmonary embolism. 2. Answer the drug information question “Can enoxaparin be used as anticoagulation for PE following the administration of alteplase?” 3. Share a tip for responding to inpatient medical emergencies. Subscribe on iTunes, Android, or Stitcher Article Half-Dose […]

In this episode, I’ll discuss iatrogenic propylene glycol toxicity. Subscribe on iTunes, Android, or Stitcher Propylene glycol is a diluent for several medications commonly used in critical care – especially diazepam, lorazepam, and phenytoin. Although propylene glycol is considered safe to use as a diluent by the FDA, the potential for toxicity exists. The potential […]

In this episode, I’ll discuss how long you continue CPR after giving IV push alteplase for pulmonary embolism related cardiac arrest. Evidence: http://jtd.amegroups.com/article/view/3595/html https://www.nejm.org/doi/full/10.1056/NEJMoa012885 Get my 6 tips for pharmacists responding to codes in my free download area at pharmacyjoe.com/free. It’s download #16. If you like this post, check out my book – A Pharmacist’s Guide […]

In this episode, I’ll discuss how to taper a dexmedetomidine infusion. To celebrate 3 years of podcasting at pharmacyjoe.com I am giving away 3 copies of my book, A Pharmacist’s Guide to Inpatient Medical Emergencies and my 6-module Code Blue and Rapid Response Training Program for Hospital Pharmacists. To enter the contest go to pharmacyjoe.com/3. […]

In this episode, I’ll discuss the continuum of depth of sedation. Subscribe on iTunes, Android, or Stitcher   The American Society of Anesthesiologists describes sedation as a continuum from minimal sedation to moderate sedation, deep sedation, and general anesthesia. The depth of sedation can be determined by evaluating the patient’s responsiveness. In a state of […]

In this episode, I’ll discuss how to tell when coag-negative staph is a pathogen. Get my 6 tips for pharmacists responding to codes in my free download area at pharmacyjoe.com/free. It’s download #16. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, […]

Subscribe on iTunes, Android, or Stitcher In this episode I’ll: 1. Discuss an article on cost effective C diff treatment. 2. Answer the drug information question “Can phenobarbital be used as monotherapy in patients with severe alcohol withdrawal?” 3. Share a tip for responding to inpatient medical emergencies Article Cost-effectiveness analysis of initial treatment strategies […]

In this episode, I’ll discuss how andexanet alpha can be used to reverse heparin. Andexanet alpha has been approved for reversal of anticoagulation from rivaroxaban and apixaban. But there is also reason to believe that andexanet alpha can be used as a reversal agent for heparin. In a 2015 in vitro study in the journal […]

In this episode, I’ll discuss the causes, treatment, and prevention of stridor. Subscribe on iTunes, Android, or Stitcher Causes Stridor is an abnormal inspiratory sound and is a sign of airway obstruction that requires immediate attention. Stridor can be caused by a mass or foreign body in the upper airway, or by laryngeal edema. Laryngeal […]

In this episode, I’ll discuss how desmopressin (DDAVP) can be used for intracranial hemorrhage. Neurocritical Care guidelines suggest consideration of a single dose of desmopressin (DDAVP) in intracranial hemorrhage associated with aspirin or ADP receptor inhibitors. Desmopressin causes the release of von Willebrand factor and increases platelet adhesion. It has a low risk of serious […]