In this episode I’ll talk about tips for the pharmacist in the initial treatment of severe sepsis / septic shock. Subscribe on iTunes, Android, or Stitcher Introduction Severe sepsis is sepsis with organ dysfunction and septic shock is sepsis induced hypotension that remains after adequate fluid resuscitation. Additional criteria for the definitions of severe sepsis […]
Episode 41: Enoxaparin in morbid obesity, morphine in dialysis, and porphyria drug database
In this episode I’ll: 1. Review an article on monitoring enoxaparin with antifactor Xa levels in morbidly obese patients 2. Answer a drug information question about using morphine in a patient on dialysis 3. Share a great resource I use for researching which medications exacerbate porphyria Subscribe on iTunes, Android, or Stitcher Article Monitoring Enoxaparin […]
Episode 40: Hyperthermia from serotonin syndrome vs malignant hyperthermia vs neuroleptic malignant syndrome
In this episode, I’ll discuss the recognition and treatment of serotonin syndrome (SS), malignant hyperthermia (MH), and neuroleptic malignant syndrome (NMS). Subscribe on iTunes, Android, or Stitcher Muscular rigidity, significant hyperthermia, and autonomic instability are all common features of serotonin syndrome, malignant hyperthermia, and neuroleptic malignant syndrome. A thorough review of the patient’s current and […]
39: Parachute use to prevent death and trauma, IV compatibility tips, and candida score calculator
In this episode I’ll: 1. Discuss an article about evidence based medicine 2. Answer a drug information question about IV compatibility 3. Share a resource for calculating a patient’s Candida Score Subscribe on iTunes, Android, or Stitcher Article Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled […]
38: Hypertensive emergency treatment
Today’s episode topic is being presented at the request of another “Pharmacy Joe” who left a voice message on pharmacyjoe.com about using clonidine for hypertensive emergencies. If you’d like to call in a topic request use the Speakpipe widget at the end of the show notes or at pharmacyjoe.com/contact. Subscribe on iTunes, Android, or Stitcher This may be […]
37: Prolonged empiric antibiotics in ICU, eosinophilic nephritis, and a 4T score calculator
In this episode I’ll: 1. Discuss an article about prolonged empiric antibiotic therapy in adult ICUs 2. Answer a drug information question about eosinophilic nephritis 3. Share a 4T score calculator Subscribe on iTunes, Android, or Stitcher Article A Multicenter Evaluation of Prolonged Empiric Antibiotic Therapy in Adult ICUs in the United States Lead Author: […]
36: Pharmacotherapy for stridor in adult ICU patients
In this episode I’ll review the definition, recognition, causes & pharmacotherapy treatments of stridor in critically ill adult patients. Subscribe on iTunes, Android, or Stitcher Defintion Stridor is an abnormal inspiratory sound, and a sign of upper airway obstruction that requires immediate attention. Recognition Stridor can be heard without a stethoscope. It is usually a […]
35: Propofol related infusion syndrome, SCIP prophylaxis Q&A, and drug induced thrombocytopenia resource
In this episode I’ll: 1. Review an article on propofol related infusion syndrome 2. Answer a drug information question about surgical antibiotic prophylaxis 3. Share a great resource I use for investigating drug induced thrombocytopenia Subscribe on iTunes, Android, or Stitcher Article Propofol infusion syndrome: a structured review of experimental studies and 153 published case […]
Episode 34: Severe hyperkalemia treatment
In this episode I’ll: 1. Review how to recognize severe hyperkalemia 2. Review the 3 categories of hyperkalemia treatments and the order which they should be used 3. Discuss the nuances of each treatment Subscribe on iTunes, Android, or Stitcher Recognizing hyperkalemia Severe hyperkalemia can be recognized by cardiac conduction abnormalities on ECG, muscle weakness […]
33: Sugammadex FDA approval and dabigatran drug interactions
In this episode I’ll: 1. Review the FDA briefing documents for sugammadex 2. Answer a drug information question about dabigatran 3. Share a great resource I use for evaluating drug interactions Subscribe on iTunes, Android, or Stitcher Before we get to the topic for today’s show I want to invite you to join the Pharmacy Nation […]
32: Why normal saline makes hyponatremia worse in SIADH
In this episode I’ll share with you what he taught me and I’ll: 1. Review the pathophysiology of hyponatremia from SIADH 2. Explain how normal saline makes it worse 3. Discuss basic treatment of severe, symptomatic hyponatremia from SIADH and what to do if you correct the sodium too fast Subscribe on iTunes, Android, or […]
31: Vanco dosing by AUC:MIC, heparin vs LMWH, and sleep hygiene resources
In this episode, I will: Review an article about monitoring vancomycin by trough levels Answer a drug information question: Why do some of my trauma patients get heparin and some enoxaparin for DVT prophylaxis? Share sleep hygiene resources that I personally use. Subscribe on iTunes, Android, or Stitcher Article Vancomycin Trough Concentration as a Predictor […]
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