In this episode, I will discuss the use of midodrine to wean ICU patients off of vasopressor infusions. Subscribe on iTunes, Android, or Stitcher At the time of this episode, I am hosting a closed beta program for my Critical Care Pharmacy Academy, a private, paid membership group where I teach other pharmacists about critical […]
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Episode 135: Levosimendan in sepsis, intubating a severe pulmonary hypertension patient, and how to become a journal peer reviewer
In this episode I’ll: 1. Discuss an article about levosimendan in sepsis. 2. Answer the drug information question “Should catecholamines be started before intubating a patient with severe pulmonary hypertension?” 3. Share a resource about how to become a peer-reviewer for a medical journal. Subscribe on iTunes, Android, or Stitcher The Critical Care Pharmacy Academy […]
Episode 134: Stress ulcer prophylaxis in critically ill patients – where are the guidelines?
In this episode, I’ll discuss stress ulcer prophylaxis in critically ill patients. Subscribe on iTunes, Android, or Stitcher Stress ulcers were first described in 1969. Stress ulcers are thought to form due to hypoperfusion to the gastric mucosa associated with critical illness. Various factors including coagulopathy, history of peptic ulcer disease, and prolonged mechanical ventilation […]
Episode 133: IV acetaminophen causes hypotension, basal PCA rates in opioid naive patients, and a resource for extracting ICD-10 codes from natural language
In this episode I’ll: 1. Discuss an article about the hemodynamic effects of IV acetaminophen in critically ill patients. 2. Answer the drug information question “When should an opioid naive patient receive a continuous basal rate on patient-controlled analgesia?” 3. Share a resource for easily extracting ICD-10 codes from natural text. Subscribe on iTunes, […]
Episode 132: Treatment of calcium channel blocker overdose in adult patients
In this episode, I’ll discuss the treatment of calcium channel blocker overdose in adult patients. Subscribe on iTunes, Android, or Stitcher Consensus recommendations for the management of calcium channel blocker poisoning in adults have been published in the journal Critical Care in October 2016. The recommendations emphasize the role of poison centers (1-800-222-1222 in […]
Episode 131: Calcium replacement may be harmful, sulfamethoxazole-trimethoprim dosing in morbid obesity, and a resource for switching to anti-XA heparin monitoring
In this episode I’ll: 1. Discuss an article about the adverse outcomes of calcium administration in critically ill patients. 2. Answer the drug information question “What dose of sulfamethoxazole/trimethoprim should be used to treat stenotrophomonas in a super-morbidly obese patient?” 3. Share a resource I’ve used to convert heparin protocols to anti-Xa monitoring. Subscribe on […]
Episode 130: Lithium toxicity
In this episode, I’ll discuss lithium toxicity. Subscribe on iTunes, Android, or Stitcher Lithium has been used since the 1970s for bipolar disorder. Toxicity from lithium may occur from an acute ingestion or when a patient on chronic lithium therapy has a decrease in renal function. Acute Patients with acute lithium ingestion primarily exhibit gastrointestinal […]
Episode 128: How to prepare a knowledge-based in-service or continuing pharmacy education lecture
In this episode, I’ll describe the steps that I follow to create knowledge-based in-services or continuing pharmacy education lectures. Subscribe on iTunes, Android, or Stitcher ACPE says this about knowledge-based education activities: These CPE activities are primarily constructed to transmit knowledge (i.e., facts). The facts must be based on evidence as accepted in the literature […]
Episode 127: Chloride content effect on patient outcomes, treatment for severe, complicated c diff, and medication identification
In this episode I’ll: 1. Discuss an article about the effect of chloride content during fluid resuscitation. 2. Answer the drug information question “What therapy is recommended for severe, complicated C. diff. infection?” 3. Share a resource for identifying medications. Subscribe on iTunes, Android, or Stitcher Article Chloride Content of Fluids Used for Large-Volume Resuscitation […]
Episode 126: Anti-xa vs aPTT for heparin infusion monitoring
In this episode, I’ll discuss using Anti-Xa vs. aPTT for heparin infusion monitoring. Subscribe on iTunes, Android, or Stitcher Over the past several years, many institutions have switched to monitoring heparin infusions with anti-factor Xa levels instead of activated partial thromboplastin time. Guidelines Expert guidelines don’t seem to take a stand either way when it […]
Episode 125: Adjusted weight dosing of heparin in obese patients, how long is glucose needed after high dose insulin therapy is stopped, and a resource for studying intensive care topics
In this episode I’ll: 1. Discuss an article about using adjusted body weight for heparin dosing in obese patients. 2. Answer the drug information question “How long is glucose therapy required after using high-dose insulin for beta-blocker or calcium channel blocker overdose?” 3. Share a resource for studying intensive care topics. Subscribe on iTunes, Android, […]
Episode 124: Causes of fever in critically ill patients
In this episode I’ll discuss causes of fever in critically ill patients. Subscribe on iTunes, Android, or Stitcher Elevated body temperature is detected in almost half of patients admitted to adult ICUs. Its presence should trigger a thorough search for the etiology. IDSA / SCCM guidelines define pyrexia in critically ill adults as a temperature […]
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