In this episode, I’ll discuss medications commonly tapered in the ICU. Subscribe on iTunes, Android, or Stitcher Three classes of medications that are frequently considered for tapering in the ICU are: -Corticosteroids -Opioids -Benzodiazepines For each of these classes, I will cover why, when, and how to taper them: Corticosteroids Why taper corticosteroids Corticosteroids are […]
Episode 173: Ciraparantag/PER977 to reverse edoxaban, how to relower serum sodium if it is corrected too fast, and a resource for intranasal medication delivery
In this episode I’ll: 1. Discuss an article about the anticoagulant reversal agent ciraparantag / PER977. 2. Answer the drug information question “How can serum sodium be re-lowered if hyponatremia is corrected too fast?” 3. Share a resource about intranasal medication delivery. Subscribe on iTunes, Android, or Stitcher Article Single-dose ciraparantag safely and completely reverses […]
Episode 172: Should SSRIs and SNRIs be discontinued in the setting of active bleeding?
In this episode, I’ll discuss whether selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs) should be discontinued in the setting of active bleeding. I am excited to announce that I have teamed up with the Wegman’s School of Pharmacy St. John Fisher College to offer ACPE Continuing Education credit for listeners of […]
Episode 171: Push-dose norepinephrine, methylene blue for vasoplegia, and a resource for hereditary angioedema
In this episode I’ll: 1. Discuss an article on push-dose norepinephrine. 2. Answer the drug information question “What is the dose of methylene blue for cardiac surgery related vasoplegia?” 3. Share a resource for hereditary angioedema. Subscribe on iTunes, Android, or Stitcher The article for this episode recently appeared in a weekly literature digest […]
Episode 170: When to use (and when not to use) tranexamic acid in critically ill patients
In this episode, I’ll discuss when to use (and when not to use) tranexamic acid in critically ill patients. Subscribe on iTunes, Android, or Stitcher Mechanism Tranexamic acid is an antifibrinolytic agent. It forms a reversible complex that displaces plasminogen from fibrin resulting in inhibition of fibrinolysis. It also inhibits the proteolytic activity of plasmin. […]
Episode 169: Platelet transfusion and hospital acquired infection, buprenorphine for methadone overdose, and a resource for toxicology emergencies
In this episode I’ll: 1. Discuss an article about platelet transfusion and hospital-acquired infection. 2. Answer the drug information question “Can buprenorphine be used in opioid overdose?” 3. Share a resource for guidance on toxicologic emergencies. Subscribe on iTunes, Android, or Stitcher Article Is platelet transfusion associated with hospital-acquired infections in critically ill patients? Lead […]
Episode 168: The case for temporarily holding lithium upon admission to the Medical/Surgical ICU
Click here to get ACPE CE credit for listening to this episode. In this episode, I’ll discuss ICU complications that could increase the risk of lithium toxicity. Starting Thursday, March 2, 2017, members of my Critical Care Pharmacy Academy will have access to my new Masterclass: Principles of infectious disease for ICU pharmacists. To learn more […]
Episode 167: Sedative requirements in stimulant users, mannitol extravasation, and an ISMP anticoagulation resource
Click here to get ACPE CE credit for listening to this episode. In this episode I’ll: 1. Discuss an article about opioid and sedative requirements in patients that use stimulants. 2. Answer the drug information question “How do you treat mannitol extravasation?” 3. Share a resource from the Institute for Safe Medication Practices on anticoagulation […]
Episode 166: Mannitol for elevated ICP (intracranial pressure)
Click here to get ACPE CE credit for listening to this episode. In this episode, I’ll discuss how to administer mannitol for elevated intracranial pressure. Subscribe on iTunes, Android, or Stitcher The definitive treatment for elevated intracranial pressure is to fix the underlying cause. Common causes are traumatic brain injury, intracranial hemorrhage, CNS infection, or […]
Episode 165: Valproate protein binding in critically ill patients, onset of angioedema after starting an ACE inhibitor, and the perfect writing instrument
Click here to get ACPE CE credit for listening to this episode. In this episode I’ll: 1. Discuss an article about valproic acid protein binding. 2. Answer the drug information question “How long after starting an ACE inhibitor does angioedema occur?” 3. Share a resource I use for writing notes. Subscribe on iTunes, Android, […]
Episode 164: Drug induced pancreatitis
Click here to get ACPE CE credit for listening to this episode. In this episode, I’ll discuss drug-induced pancreatitis. Subscribe on iTunes, Android, or Stitcher The Critical Care Pharmacy Academy is a place for pharmacists and pharmacy residents to gain practical critical care knowledge and skills. Inside the Academy you will find monthly Masterclasses, weekly […]
Episode 163: Apixaban vs warfarin in severe renal impairment, methylprednisolone for intraoperative spinal cord injury, and a resource for CMS – TJC quality measures
Click here to get ACPE CE credit for listening to this episode. In this episode I’ll: 1. Discuss an article comparing apixaban with warfarin in patients with severe renal impairment. 2. Answer the drug information question “Should high dose methylprednisolone be given for intraoperative spinal cord injury?” 3. Share a resource for understanding CMS quality […]
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