Episode 217: How to dose lipid emulsion for enteral drug toxicity

You can watch or listen to this episode on my youtube channel:

 

Reference: American College of Medical Toxicology published guidance for using ILE

How to get around the 999 mL/hr max rate on most smart pumps to deliver 0.25mL/kg/min lipid emulsion over 3 minutes

The same total ILE dose that 0.25 mL/kg/min over 3 minutes provides can be infused as follows using conventional “smart” pumps:

~ 70 kg patient = 20% IV lipid emulsion at 999 mL/hr for 3 minutes

~ 90 kg patient = 20% IV lipid emulsion at 999 mL/hr for 4 minutes

~ 110 kg patient = 20% IV lipid emulsion at 999 mL/hr for 5 minutes

After the high-dose infusion is complete, the rate can be dropped to 0.025 mL/kg/min as the guidelines recommend for the remainder of treatment.

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If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies.

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