In this episode, I’ll discuss acetazolamide’s use as a respiratory stimulant in ICU patients. Subscribe on iTunes, Android, or Stitcher Acetazolamide is a carbonic anhydrase inhibitor that has indications for use in altitude sickness, edema, and elevated intraocular pressure. However, acetazolamide also has potentially useful properties as a respiratory stimulant for certain ICU patients. Patients […]
Episode 727: Dealing with and preventing negative interactions with other professionals
In this episode, I’ll discuss dealing with and preventing negative interactions with other professionals. Subscribe on iTunes, Android, or Stitcher We’ve all been yelled at or had a professional interaction go sour at some point in our career. Perhaps it was when trying to deliver a recommendation to a physician, ask a question of a […]
Episode 726: Why can’t Paxlovid be crushed?
In this episode, I’ll discuss Paxlovid and other novel dosage forms that should not be crushed but look like they can be. Subscribe on iTunes, Android, or Stitcher One of the worst phrases in a medication’s prescribing information is “do not do ___” without an explanation of why. This is because without a “why” clinicians […]
Episode 725: Clinically relevant pharmacokinetic knowledge on antibiotic dosing (part 3 of 3)
In this episode, I’ll discuss the final 4 questions of a recent survey of intensive care professionals about clinically relevant pharmacokinetic knowledge on antibiotic dosing. This is part 3 of a 3 part series that began with episode 723. Subscribe on iTunes, Android, or Stitcher The survey was published in May 2019 in the journal […]
Episode 724: Clinically relevant pharmacokinetic knowledge on antibiotic dosing (part 2 of 3)
In this episode, I’ll discuss questions 6, 7 and 8 of a recent survey of intensive care professionals about clinically relevant pharmacokinetic knowledge on antibiotic dosing. This is part 2 of a 3 part series that began with episode 723. Subscribe on iTunes, Android, or Stitcher The survey was published in May 2019 in the […]
Episode 723: Clinically relevant pharmacokinetic knowledge on antibiotic dosing (part 1 of 3)
In this episode, I’ll discuss a survey of intensive care professionals about clinically relevant pharmacokinetic knowledge on antibiotic dosing. Subscribe on iTunes, Android, or Stitcher Article Clinically relevant pharmacokinetic knowledge on antibiotic dosing among intensive care professionals is insufficient: a cross-sectional study Lead author: Lucas M. Fleuren Published May 2019 in the journal Critical Care This […]
Episode 722: Can a urine dipstick test identify patients with clinically significant amounts of plasma DOAC levels?
In this episode, I’ll discuss whether a urine dipstick test can identify patients with clinically significant amounts of plasma DOAC levels. Subscribe on iTunes, Android, or Stitcher Direct Acting Oral Anticoagulants such as apixaban, rivaroxaban, edoxaban, and dabigatran do not have readily available assays, yet there is often a clinical need to determine the presence […]
Episode 721: The benefits of a pharmacy-driven medication history
In this episode, I’ll discuss the benefits of a pharmacy-driven medication history. Subscribe on iTunes, Android, or Stitcher The concept of specialization in medicine to achieve superior results has been prevalent for more than 100 years and is rarely subjected to scrutiny. However with a modern focus on evidence-based medicine, to change the way a […]
Episode 720: Strategies to reduce the cost of using vasopressin
In this episode, I’ll discuss strategies to reduce the cost of using vasopressin. Subscribe on iTunes, Android, or Stitcher After a period of unstable supply, IV vasopressin was given approval by the FDA in 2014 to be sold under the brand name Vasostrict by a single manufacturer. While this change went a long way to […]
Episode 719: Peripheral Vasopressor Feasibility
In this episode, I’ll discuss the feasibility of peripheral vasopressors. Subscribe on iTunes, Android, or Stitcher Vasopressors are traditionally administered via central line only due to concerns about extravasation and tissue damage when they are given via a peripheral line. However central lines can be time consuming to place and have a risk of complication […]
Episode 718: Is that gabapentin just temporary?
In this episode, I’ll discuss the continuation of newly prescribed gabapentin for acute pain management after hospital discharge. Subscribe on iTunes, Android, or Stitcher The frequency of gabapentin use for the treatment of inpatient postoperative pain has increased due to the promotion of multimodal analgesia with the goal of reducing the use of opioids. A […]
Episode 717: The case for continuing statins for patients admitted to the ICU
In this episode, I’ll discuss the case for continuing statins for patients admitted to the ICU. Subscribe on iTunes, Android, or Stitcher Nonpharmacologic therapy remains the mainstay for the prevention of delirium in ICU patients. Statins are among the many medications that have been studied for the treatment and prevention of ICU delirium, and they […]
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