In this episode, I’ll discuss the use of etomidate in the ICU. Subscribe on iTunes, Android, or Stitcher To celebrate the 200th episode of the elective rotation podcast, I am giving away 10 copies of my book, A Pharmacist’s Guide to Inpatient Medical Emergencies. You can win a copy by heading over to my new Facebook page. […]
Episode 199: Withholding stress ulcer prophylaxis in critically ill patients, can pancrelipase pellets be given via gastrostomy tube, and a resource from Vanderbilt University School of Medicine
In this episode I’ll: 1. Discuss an article about withholding stress ulcer prophylaxis in critically ill patients. 2. Answer the drug information question “Can pancrelipase pellets be given via gastrostomy tube?” 3. Share a resource from Vanderbilt University School of Medicine. Subscribe on iTunes, Android, or Stitcher Article Withholding Pantoprazole for Stress Ulcer Prophylaxis in […]
Episode 198: How to use high dose insulin therapy for beta-blocker or calcium channel blocker overdose
In this episode, I’ll discuss how to use high dose insulin therapy for beta-blocker or calcium channel blocker overdose. Subscribe on iTunes, Android, or Stitcher An overdose of beta-blockers or calcium channel blockers often induces life-threatening cardiogenic shock. Traditional therapies for beta-blockers or calcium channel blocker toxicity are: Glucagon Calcium Atropine Electricity (pacing) Vasopressors Unfortunately, […]
Episode 197: Delay in the 2nd dose of antibiotic for septic patients, is it OK to give lactated ringers to a septic patient with elevated lactate, and a resource for learning about rare disorders
In this episode I’ll: 1. Discuss an article about delays in the 2nd dose of antibiotic for septic patients. 2. Answer the drug information question “Is it OK to give lactated ringers to a septic patient with elevated lactate?” 3. Share a resource for learning about rare disorders. Subscribe on iTunes, Android, or Stitcher Article […]
Episode 196: How to easily perform a Monte Carlo Simulation in under 10 minutes using Microsoft Excel, Apple Numbers or Google Sheets
In this episode, I will discuss how to easily perform a Monte Carlo Simulation in under 10 minutes using Microsoft Excel, Apple Numbers or Google Sheets. Subscribe on iTunes, Android, or Stitcher What is Monte Carlo Simulation? A Monte Carlo Simulation in the context of healthcare uses software to simulate thousands of patients from smaller […]
Episode 195: Is allometric dosing of vancomycin likely to achieve AUC/MIC ratio over 400?
In this episode, I’ll discuss whether allometric dosing of vancomycin is likely to achieve AUC/MIC ratio over 400. Subscribe on iTunes, Android, or Stitcher In episode 193, I discussed an article about allometric dosing of vancomycin. In a single-center retrospective study, the allometric vancomycin dosing regimen achieved therapeutic vancomycin concentrations 77% of the time. […]
Episode 194: Interaction between valproic acid and carbapenem antibiotics – should it be considered contraindicated in ICU patients?
In this episode, I’ll discuss the interaction between valproic acid and carbapenem antibiotics. Subscribe on iTunes, Android, or Stitcher Since the late 1990s, it has been known that carbapenem antibiotics lower plasma concentrations of valproic acid. The level of significance for this interaction varies between different references. Most drug interaction references list the combination of […]
Episode 193: Allometric vancomycin dosing, how long to give steroids be given for severe alcoholic hepatitis, and an allometric vancomycin dosing calculator
In this episode I’ll: 1. Discuss an article about allometric dosing of vancomycin. 2. Answer the drug information question “How long should steroids be given for severe alcoholic hepatitis?” 3. Share a resource for calculating the allometric dosing of vancomycin. Article Allometric versus consensus guideline dosing in achieving target vancomycin trough concentrations Lead author: Matthew […]
Episode 192: Sodium bicarbonate alternatives due to the current shortage
In this episode, I’ll discuss the alternatives to sodium bicarbonate given the current drug shortage. Subscribe on iTunes, Android, or Stitcher This isn’t the first time we’ve had to deal with a sodium bicarbonate shortage. Back in 2012 there was also a bicarb shortage…but this time it is more complicated. The two alternatives to sodium […]
Episode 191: Effects of IV push administration on beta-lactam pharmacodynamics, duration of octreotide in variceal bleeding, and a video based resource
In this episode I’ll: 1. Discuss an article about the effects of IV push administration on beta-lactam pharmacodynamics. 2. Answer the drug information question “How long should octreotide be continued in patients with variceal bleeding?” 3. Share a video-based resource that explains complex ICU topics to patients and students. Subscribe on iTunes, Android, or Stitcher […]
Episode 190: Do patients taking warfarin for atrial fibrillation require bridging?
In this episode, I’ll discuss whether patients taking warfarin for atrial fibrillation require bridging. Subscribe on iTunes, Android, or Stitcher Background For almost 10 years, guidelines have recommended bridge therapy for patients taking warfarin for atrial fibrillation. When anticoagulation needs to be temporarily withheld, bridge therapy with a shorter-acting anticoagulant is used to reduce the […]
Episode 189: Preventing post-extubation stridor, giving ceftriaxone for variceal bleeding, and a resource for antibiotic information
In this episode I’ll: 1. Discuss an article about post-extubation stridor. 2. Answer the drug information question “Why should patients with variceal bleeding receive ceftriaxone?” 3. Share a resource for antibiotic information. Subscribe on iTunes, Android, or Stitcher The article for this episode recently appeared in a weekly literature digest for members of my Critical […]
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