Objectives: 1. Describe the trough levels associated with voriconazole toxicity 2. Recall the evidence behind concerns for toxicity when using IV voriconazole in renal failure

Objectives: 1. Describe the mechanisms of heparin resistance 2. Recall the management strategies available for suspected heparin resistance

Objectives: 1. Describe the rationale for upgrading evidence in cancer-related VTE treatment 2. Recall the 4 new recommendations in the Chest VTE guidelines

Objectives: 1. Describe the evidence behind why anaerobes are not likely the major pathogens in aspiration pneumonia 2. Recall the CAP Guidelines recommendations on aspiration pneumonia

Objectives: 1. Describe the causative agents in most reported “iodine” allergies 2. Recall 2 strategies for premedication of iodanated contrast media

Objectives: 1. Describe the difference in MAP goal recommendations between the 2016 and 2021 sepsis guidelines 2. Recall the dose level of norepinephrine at which adding vasopressin is recommended

Objectives: 1. Describe the expected outcomes from the use of ketamine and propofol for procedural sedation over propofol alone 2. Recall the dose ratios used in most RCTs for ketamine:propofol

Objectives: 1. Describe the recommendations on double coverage in 3 major IDSA guidelines 2. Recall risk factors for MDR gram negative pathogens

Objectives: 1. Describe the incidence of angioedema and intracranial hemorrhage to alteplase 2. Recall the steps to take if intracranial hemorrhage occurs

Objectives: 1. Describe the dose and frequency used for alternative meropenem strategies 2. Recall the renal dose adjustment cutoffs when using the 500 mg every 6 hour intermittent regimen

Objectives: 1. Describe the indication for using steroids in a patient with sepsis 2. Recall the dose of norepinephrine at which vasopressin should be added

Objectives: 1. Describe the ISBAR communication method 2. Recall the 4 possible outcomes of an intervention