Objectives: 1. Describe the conflicting evidence behind the ROSE and ACURASYS trials 2. Recall the recommendations of the ESICM Guidelines on NMBA use as well as 3 potential legitimate use cases for NMBAs in ARDS

Objectives: 1. List the poisoning scenarios where lipid emulsion is unlikely to provide a benefit 2. Recall the poisoning scenarios when high dose insulin is first line therapy

Objectives: 1. Describe how the pharmacokinetics of azithromycin can support discontinuation before 5 days of therapy. 2. Recall the reasoning behind the IDSA CAP Guideline not recommending routine legionella urine antigen testing.

Objectives: 1. Recall the 4 types of immune mediated allergic reactions 2. Recall the purpose of implementing a screening tool from a stewardship point of view 3. Recall the differences between the 12 and 16 step desensitization protocols

Objectives: 1. Describe the randomized and retrospective trials that have evaluated half dose alteplase. 2. Recall the 3 major PE treatment guidelines and their position on half dose alteplase.

Objectives: 1. Describe the benefits and drawbacks of fixed dosing of 4-factor prothrombin complex concentrate for warfarin reversal. 2. Recall the major issues in fixed dosing of 4-FPCC that consensus must be reached on before a protocol can be finalized.

Objectives: 1. Describe the causes of iatrogenic hyperchloremia 2. Recall the evidence behind available prevention strategies for each possible cause of iatrogenic hyperchloremia

Objectives: 1. Recall the possible drug-related causes of new fever in an ICU patient 2. Describe the role of procalcitonin and C-reactive protein in the evaluation of new fever

Objectives: 1. Recall the different levels of evidence supporting the 11 guideline statements 2. Describe the role for albumin, isotonic saline, and balance electrolyte solutions as resuscitation fluids in critically ill patients

Objectives: 1. Recall which purge solution base fluids are commonly used and which are contraindicated. 2. Describe a possible pharmacologic treatment for device thrombosis.

Objectives: 1. Recall the risk factors for stress-related upper GI bleeding 2. Describe the recommended medication, dose, and route of administration for stress ulcer prophylaxis

Objectives: 1. Recall the diagnostic criteria for neuroleptic malignant syndrome 2. Describe the commonly used general and specific treatments for critically ill patients with NMS