Objectives: 1. Describe the necessary requirements in the 3 categories ASHP uses to qualify PGY-1 residency preceptors 2. Recall the most common and practical ways to meet the ASHP qualification requirements for preceptors
IDSA Prolonged Beta Lactam Infusion Guidelines Evidence Review
Objectives: 1. Describe the evidence supporting the major guideline recommendations for prolonged infusion beta lactams 2. Recall the real-world implications of guideline recommendations that are conditional and based on very low quality evidence
Evidence Behind NMBA Use in ARDS Guidelines
Objectives: 1. Describe the conflicting evidence behind the ROSE and ACURASYS trials 2. Recall the recommendations of the ESICM Guidelines on NMBA use as well as 3 potential legitimate use cases for NMBAs in ARDS
Updates to AHA Guidelines on Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning
Objectives: 1. List the poisoning scenarios where lipid emulsion is unlikely to provide a benefit 2. Recall the poisoning scenarios when high dose insulin is first line therapy
De-Escalation of Empiric Atypical Coverage with Azithromycin in CAP
Objectives: 1. Describe how the pharmacokinetics of azithromycin can support discontinuation before 5 days of therapy. 2. Recall the reasoning behind the IDSA CAP Guideline not recommending routine legionella urine antigen testing.
Penicillin Allergy Cross-Reactivity, Screening Tools, and Desensitization
Objectives: 1. Recall the 4 types of immune mediated allergic reactions 2. Recall the purpose of implementing a screening tool from a stewardship point of view 3. Recall the differences between the 12 and 16 step desensitization protocols
Half Dose Alteplase for Pulmonary Embolism
Objectives: 1. Describe the randomized and retrospective trials that have evaluated half dose alteplase. 2. Recall the 3 major PE treatment guidelines and their position on half dose alteplase.
Building an Evidence-Based Fixed-Dose 4-FPCC Warfarin Reversal Protocol
Objectives: 1. Describe the benefits and drawbacks of fixed dosing of 4-factor prothrombin complex concentrate for warfarin reversal. 2. Recall the major issues in fixed dosing of 4-FPCC that consensus must be reached on before a protocol can be finalized.
Understanding and Preventing Iatrogenic Hyperchloremia
Objectives: 1. Describe the causes of iatrogenic hyperchloremia 2. Recall the evidence behind available prevention strategies for each possible cause of iatrogenic hyperchloremia
Understanding the SCCM/IDSA Guidelines for New Fever in a Critically Ill Adult
Objectives: 1. Recall the possible drug-related causes of new fever in an ICU patient 2. Describe the role of procalcitonin and C-reactive protein in the evaluation of new fever
Guidelines on Choosing Resuscitation Fluids
Objectives: 1. Recall the different levels of evidence supporting the 11 guideline statements 2. Describe the role for albumin, isotonic saline, and balance electrolyte solutions as resuscitation fluids in critically ill patients
Pharmacotherapy Considerations with the Impella Ventricular Assist Device
Objectives: 1. Recall which purge solution base fluids are commonly used and which are contraindicated. 2. Describe a possible pharmacologic treatment for device thrombosis.
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