Objectives: 1. Describe the 3 common pathogens that produce exotoxins which increase their virulence. 2. Recall the commonly recommended adjunctive antibiotics for toxin inhibition and their usual duration of therapy.

Objectives: 1. Describe the 5 microskills of the one minute preceptor technique 2. Recall the two opportunities to provide meaningful feedback to the learner when using the one minute preceptor technique

Objectives: 1. Recall the relative accuracy of the Cockcroft Gault formula with the 2021 race-free eGFR formulas published by NKF 2. Describe the rationale for using eGFR to make medication dose adjustment decisions

Objectives: 1. Describe the pathophysiology of mucus dysfunction in critically ill patients. 2. Recall the commonly used mucolytics and the evidence that supports their use.

Objectives: 1. Recall the evidence supporting melatonin use in ICU patients 2. Describe the benefits and risks of using dexmedetomidine over propofol for light sedation in the ICU

Objectives: 1. Recall the benefits of using a blended strategy of trough-based and AUC:MIC-based vancomycin dosing 2. Describe the types of patients that should have one and two-level Bayesian AUC:MIC-based vancomycin dosing

Objectives: 1. Recall what to ask the charge nurse before you begin pre-rounding 2. Describe the main categories to focus on when pre-rounding time is less than ideal

Objectives: 1. Recall the historical and new definitions of massive transfusion 2. Describe why hypocalcemia may occur in patients undergoing massive transfusion

Objectives: 1. Recall a loop diuretic dose escalation technique 2. Describe the two metabolic derangements to monitor for when using loop diuretics for deresuscitation

Objectives: 1. Describe the 4-step approach to empiric antibiotic selection for patients with complicated UTI. 2. Recall the recommended duration of therapy for patients with complicated UTI.

Objectives: 1. Recall which post arrest patients should not receive antiseizure prophylaxis 2. Describe the considerations in how long to continue CPR after giving a fibrinolytic for cardiac arrest due to pulmonary embolism

Objectives: 1. List the poisoning scenarios where high-dose insulin is first-line therapy 2. Recall the poisoning scenarios when rapid sedation is necessary to avoid physical restraints